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EZH2 suppresses ferroptosis in hepatocellular carcinoma and reduces sorafenib sensitivity through epigenetic regulation of TFR2
The discovery of the RNA-binding proteins Guanine-rich sequence binding factor 1 (Grsf1) and Parkinsons disease-related protein DJ-1, which both bind the extended 5UTR of the GPx4 mRNA supports this idea (Ufer et al., 2008
J.HaqueJ.McMahanR
The variety of biomarkers investigated (hormones, proteins, amino acids, lipid profile, immune-related biomarkers, and even fructose, mannose and vitamin D) highlights both the complexity and limited understanding of the condition
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